ceesdekker.net - An Overview

ceesdekker.net - An Overview

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‘Of course, which is about ideal. I look for a Bodily idea of biological programs inside of a bottom-up way. I feel you could potentially distinguish three traces of exploration in my group in the meanwhile. The primary worries chromosome structure: How can you have a metre-long DNA polymer folded and organised in such a microscopic mobile? We have made visualisation techniques that enable us to review how, such as, SMC proteins loop DNA (online video on Youtube) to be able to Create up chromosomes.

Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules

The subsequent article content are merged in Scholar. Their merged citations are counted only for the initial post.

Nanofabrication of electrodes with sub-five nm spacing for transportation experiments on single molecules and metal clusters

2015, discovery that condensin is usually a hugely flexible protein composition; and 1st detection of DNA knots making use of nanopores

Example (three) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is shown in gray, the rim in the pore is highlighted in red, and also a 3D rendering in the motion with the DNA rod is displayed.

What distinguishes biology from chemistry is the fact these components jointly make up a living process. The secret of claimed lifestyle, I feel, lies within the interactions, the interaction of those molecules. The large dilemma with regards to the origin of life remains to be unanswered. How did we at any time evolve from easy molecules in the very intricate systems we see right now? We have no idea. I would like to operate on These types of large, open up thoughts.’

Atomic pressure microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative vogue

‘Indeed, I fully grasp people today were shocked at time. At the conclusion of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I've to confess that it experienced turn into a little bit bored, I didn’t learn A lot any more. The sector went far more into the appliance aspect, how you could possibly combine nanotubes into Digital circuits.

But carbon nanotubes have remained a investigate subject of sizeable curiosity to lots of. Without a doubt, the outlook on using carbon nanotubes to develop practical products, in areas for example radio-frequency electronics, digital electronics and flexible electronics, continues to be vibrant.

‘The concept there is such a point for a commencing, a big bang, is currently an interesting signpost to take into consideration that there was a creator. But more typically, and on The idea of pure rationality, I also arrive at a Christian interpretation of fact. An atheistic worldview is often a naturalistic worldview: essentially, there are actually only cees dekker atoms and natural forces that we are able to measure.

1999, to start with measurement in the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for your new Luttinger description of interacting electrons in nanotubes

2005, discovery with the mechanism of DNA uncoiling by topoisomerase enzymes; discovery of prolonged-range conformational alterations in Mre11/DNA repair complexes; and 1st force measurements on the DNA molecule in a very nanopore

‘I am driven by marvel and questions. On a material level I discover answers in physics, but I expertise my deepest joy with God. That faith also drives my science And the way I handle folks.